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Journal of Pharmaceutical and BioSciences

 
Year : 2015   |  Volume : 3  |  Issue : 1  |  Page : 1-7

Solid Lipid Nanoparticle: UV Protection

Ghadigaonkar P, Prabhavalkar K
Sunscreen formulation, safety is of high importance because of the diminishing ozone layer. Solid lipid nanoparticles are introduced as the new generation of carrier for cosmetics, especially for UV blockers. The efficiency of a cosmetic product depends not only on the active ingredients but also on the carrier systems involved, with the aim to improve its bioavailability, photoprotection and photostability. Thus the emergence of SLN has recently used in preparation of sunscreen and as an active carrier for organic and inorganic sunscreen agents to optimize UV protection and it acts as an active carrier for sunscreens since they represent physical sunscreen on their own. Thus the incorporation of molecular sunscreen into SLN has a synergistic photoprotection effect. The improving blocking activity allows reduction of concentration of UV blocker. While the benefits of regular use of sunscreen are undisputed, some adverse effects of these organic UV blockers have been reported due to penetration into particulate drug delivery system each as solid lipid nanoparticle while maintaining the protective level of conventional formulation.
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