Plumeria alba is small laticiferous tree or shrub is a native of tropical America, commonly known as White Champa Leaf and stem were evaluated for its phytoconstituents, which is used in several traditional medicines to cure various diseases. The plant is mainly grown for its ornamental and fragrant flowers, are also known for their medicinal importance. Leaves arrangement is lanceolate to oblanceolate with white flowers, fragrant in corymbose fascicles, and fruit is edible. Their medicinal properties are often due to their latex which is frequently drastic and corrosive. Latex is applied to ulcers, herpes, and scabies. Seeds possess hemostatic properties. Moreover, its bark is bruised and applied as plaster over hard tumors. Whereas the others finds use as purgative, cardiotonic, diuretic, and hypotensive. The medicinal value of this Plumeria species in the treatment of a large number of human ailments is mentioned in Ayurveda, Charaka Samhita, and Sushrita Samhita. For millennia, the Indian population has depended mainly on plant-based crude drugs for a variety of ailments. This alternative system of medicine is gaining increasing popularity worldwide.

DOI: 10.31555/jpbs/2018/6/1/1-4

The intent of research was to formulate and evaluate controlled release drug delivery system of ocusert of prednisolone sodium phosphate, corticosteroid for the treatment of viral conjunctivitis. Ocusert are sterile preparation having drug as dispersion or as solution in the polymeric base. Ocusert were formulated using different polymers such as hydroxypropyl methyl cellulose E-15, ethyl cellulose, and Eudragit RL-100 at various concentrations and combinations. Films were prepared by mercury casting method using different ratios of polymers. Selected physiochemical properties such as thickness, weight, percentage moisture absorption, and in-vitro release pattern of Prednisolone sodium phosphate ocusert were studied and reported

DOI: 10.31555/jpbs/2018/6/1/5-8

Antioxidants are emerging as prophylactic and therapeutic agents for various diseases. The present study deals with an antioxidant potential of methanolic and aqueous extract of Albizia lebbeck leaves. The antioxidant potential of methanolic and aqueous extract of A. lebbeck leaves was investigated by employing two in vitro methods, such as Nitric oxide radical scavenging activity and reducing power assay. Results obtained in the present study reveal methanolic extract of A. lebbeck possesses significant antioxidant activity as compared to aqueous extract.

DOI: 10.31555/jpbs/2018/6/1/9-12